Vyacheslav Mikhailov was born in the remote village of Arzgir, located in the Stavropol region. After serving in the army, Mikhailov attended the Repin Institute of Painting, Sculpture and Architecture in Leningrad where he studied under the renowned art professor Yevsey Moisejenko.
After completing his post-graduate studies in 1979, Mikhailov, along with Valery Lukka (also an Academy of Arts graduate) and Felix Volosenkov, founded an art group, later named by art critics The Three Bogatyrs, devoted to searching for new ways of expression.
In the early 1980’s Mikhailov began participating in various exhibitions, both in Russia and abroad in Europe, China and America. He had a solo exhibition at the Russian State Museum in 1995 and contributed to a group exhibition at the Hermitage Museum in 2004. He is a member of the Russian Association of Artists and a member of the State Artists Association of Italy, "ITALART". He was also awarded the title of `Honoured Artist of Russia'.